Tortuous extracranial arteries contribute to white Matter hyperintensities in aging brains
These findings highlight the role of extracranial arterial tortuosity in WMH burden and reveal sex-specific differences in vascular vulnerability. The results underscore the need for further investigation into how age-related vascular remodeling contributes to WMH development and cognitive decline.
Authors
- Arjun V. Masurkar (ORCID: https://orcid.org/0000-0002-2498-2059)
- Marco Muccio (ORCID: https://orcid.org/0000-0003-1559-7113)
- Yulin Ge (ORCID: https://orcid.org/0000-0002-2320-6031)
- Thomas Wısnıewskı (ORCID: https://orcid.org/0000-0002-3379-8966)
- Chenyang Li (ORCID: https://orcid.org/0000-0003-4244-8615)
- Zhe Sun (ORCID: https://orcid.org/0000-0002-6043-8675)
Institutions
- Center for Neuro-Oncology (US)
- New York University (US)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2025-10-09
- DOI
- https://doi.org/10.3389/fnagi.2025.1641214
- Citations
- 1
- Primary Topic
- Cerebrovascular and Carotid Artery Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.52