Atopic Comorbidities Associated With Chronic Spontaneous Urticaria: A Case‐Control Analysis of the All of Us Research Program
This study demonstrates a strong association between CSU and atopic disease in a racially and socioeconomically diverse cohort. Our findings highlight shared Th2-driven pathways underlying CSU and atopy and reinforce the potential utility of type 2 targeted therapies (e.g., dupilumab) in patients with CSU and comorbid atopic disease. Clinicians should screen CSU patients for atopic disease to help guide comprehensive, targeted therapy.
Authors
- Francesco Delacqua
- Reid Oldenburg
- Savannah K. Fakhouri
- Julian A. Cortes (ORCID: https://orcid.org/0009-0003-8702-3458)
- Nana Ama Adjei‐Frimpong (ORCID: https://orcid.org/0009-0007-2929-0207)
Institutions
- University of San Diego (US)
- University of California San Diego (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- JEADV Clinical Practice
- Published
- 2025-10-08
- DOI
- https://doi.org/10.1002/jvc2.70181
- Primary Topic
- Urticaria and Related Conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00