Angiofibroma at Unusual Site - A Case Report

Angiofibroma is an uncommon benign mesenchymal neoplasm of soft tissue, first described in 2012 and recognized in the 2020 World Health Organization classification of soft tissue and bone tumors. It has different locations and the diagnosis is suggested by clinical evaluation and imaging findings, and confirmed by histopathological examination of the excised specimen. Microscopically, it appears as a well-circumscribed tumor composed of bland spindle cells within a variably collagenous to myxoid stroma, permeated by a rich network of thin-walled blood vessels. Because of its variable morphology and absence of specific immunohistochemical markers, angiofibroma often poses a broad differential diagnosis. We present the case of a 52-year-old male with an abdominal mass, diagnosed as angiofibroma based on histopathological and immunohistochemical findings..