Prospective surveillance reveals high rates of antimicrobial resistance in urinary tract infections among patients with cirrhosis.
The study highlights alarming antimicrobial resistance, particularly in nosocomial UTIs. Traditional antibiotics, such as ceftriaxone for community-acquired UTIs and carbapenems or piperacillin/tazobactam for nosocomial infections, fail to provide sufficient empirical coverage. More comprehensive approaches to empirical treatment, such as combination therapies or newer antibiotics targeting resistant pathogens, are needed.
Authors
- Josefina Pagés (ORCID: https://orcid.org/0000-0002-1167-7047)
- Maximiliano Gabriel Castro (ORCID: https://orcid.org/0000-0003-0112-8455)
- Antonio Santo (ORCID: https://orcid.org/0009-0003-7099-7862)
- Melisa Dirchwolf (ORCID: https://orcid.org/0000-0002-9083-3561)
- Adrian Carlos Gadano (ORCID: https://orcid.org/0000-0002-3590-2472)
- Astrid Smud
- Alina Zerega
- Jesica Tomatis
- Lorena Notari
- Manuel Mendizábal (ORCID: https://orcid.org/0000-0002-7026-9908)
- María Dolores Murga
- Gonzalo Gómez Perdiguero (ORCID: https://orcid.org/0000-0002-6026-9656)
- Pablo Calzetta
- Gisela Gualano
- María Laura Garrido (ORCID: https://orcid.org/0000-0003-1071-6603)
- Sebastián Marciano (ORCID: https://orcid.org/0000-0002-7983-1450)
- Margarita Anders (ORCID: https://orcid.org/0000-0002-2238-5322)
- Diego Hernan Giunta (ORCID: https://orcid.org/0000-0002-8427-6033)
- Fernando Cairo (ORCID: https://orcid.org/0000-0003-2480-417X)
- Julia Brutti
- Carolina Vázquez (ORCID: https://orcid.org/0000-0003-2834-9047)
- Anabel Romero (ORCID: https://orcid.org/0000-0001-8017-1501)
- Esteban González Ballerga (ORCID: https://orcid.org/0000-0002-8066-2244)
- Martín Elizondo (ORCID: https://orcid.org/0000-0001-8396-6588)
- Ana Palazzo
- Diego Arufe
- Brenda Osso Sánchez
- Natalie Vilcinskas
- Camila Maria Briz (ORCID: https://orcid.org/0009-0005-5615-832X)
- Ilse Sorena Pardo Ivirico
Institutions
- University of Mendoza (AR)
- National University of Tucumán (AR)
- Hospital Italiano de Buenos Aires (AR)
- National University of Santiago del Estero (AR)
- Centro Científico Tecnológico - Santa Fe (AR)
- Hospital Quirónsalud Sagrado Corazón (ES)
- Hospital Fernández (AR)
- Hospital Universitario Austral (AR)
- Centro Científico Tecnológico - San Luis (AR)
- Hospital de Clínicas "José de San Martín" (AR)
- Instituto Universitario de la Policía Federal Argentina (AR)
- Hospital Alemán (AR)
- Hospital Central de las Fuerzas Armadas (UY)
- Hospital El Cruce (AR)
- Hospital Privado (AR)
- Fundacion Allende (AR)
Publication Details
- Journal
- Annals of Hepatology
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1016/j.aohep.2025.102135
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00