Dose-response immunomodulatory effects of Mesenchymal stem cell-derived culture-conditioned media in acute Graft-versus-Host Disease
These results emphasize the critical role of optimizing CCM collection timing and concentration to maximize therapeutic potential. Our study paves the way for the development of standardized, scalable, and effective cell-free therapies for aGVHD.
Authors
- Sameer Bakhshi (ORCID: https://orcid.org/0000-0001-9367-4407)
- Mukul Aggarwal (ORCID: https://orcid.org/0000-0002-9885-1625)
- Deepam Pushpam (ORCID: https://orcid.org/0000-0001-8222-331X)
- Sujata Mohanty (ORCID: https://orcid.org/0000-0002-0047-4914)
- Ritu Gupta (ORCID: https://orcid.org/0000-0001-5364-4086)
- Vatsla Dadhwal (ORCID: https://orcid.org/0000-0003-0280-5833)
- Sandeep Rai (ORCID: https://orcid.org/0000-0003-1858-6081)
- Meenakshi Mendiratta
- Ranjit Kumar Sahoo (ORCID: https://orcid.org/0000-0002-4130-724X)
- Aditya Gupta (ORCID: https://orcid.org/0000-0002-3730-8944)
- Mohini Mendiratta
Institutions
- DR. B.R.A. Institute Rotary Cancer Hospital (IN)
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- Regenerative Therapy
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1016/j.reth.2025.10.001
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00