Molecular profiling in paediatric hepatocellular adenomas: phenotypic correlations and clinical significance
Paediatric HCAs arise in diverse clinical contexts and may require individualized treatment planning. While histologic and immunophenotypic evaluation is sufficient in most cases, molecular profiling adds value in diagnostically challenging scenarios and may help guide management decisions.
Authors
- Yan Zhou (ORCID: https://orcid.org/0000-0002-9867-5828)
- Xuchen Zhang (ORCID: https://orcid.org/0000-0002-1484-4672)
- Alanna J. Church (ORCID: https://orcid.org/0000-0002-4835-5770)
- Juan Putra (ORCID: https://orcid.org/0000-0002-3487-4641)
- Allison F. O’Neill (ORCID: https://orcid.org/0000-0002-8957-3870)
- Antonio R. Pérez‐Atayde (ORCID: https://orcid.org/0000-0001-8036-6288)
Institutions
- Boston Children's Hospital (US)
- Harvard University (US)
- Yale University (US)
- Dana-Farber/Boston Children's Cancer and Blood Disorders Center (US)
Publication Details
- Journal
- Histopathology
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1111/his.70019
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00