In vitro and in vivo biocompatibility of a porcine cholecystic extracellular matrix (CECM) membrane for tissue regeneration
The porcine CECM membrane demonstrated favorable physicochemical properties, excellent cytocompatibility, enhanced wound healing potential, and superior tissue integration characteristics compared to commercial GTR membranes. These preliminary findings provide a strong scientific foundation supporting the development of the GTR membrane for periodontal regenerative therapy.
Authors
- Sukumaran Anil (ORCID: https://orcid.org/0000-0002-6440-8780)
- Mekha Grace Varghese
- Yogesh Bharat Dalvi (ORCID: https://orcid.org/0000-0001-7683-3146)
- Rani Shine Raju
- Nibu Varghese
- Nebu George Thomas (ORCID: https://orcid.org/0000-0001-8679-7783)
- Avneesh Chopra (ORCID: https://orcid.org/0000-0001-7706-3577)
- Kanakarajan V. Pratheesh (ORCID: https://orcid.org/0000-0002-0242-0872)
- Thomas George Velliavettil
- Betcy Thomas
Institutions
- Sree Chitra Thirunal Institute for Medical Sciences and Technology (IN)
- Pushpagiri Medical College (IN)
- Humboldt-Universität zu Berlin (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- Medizinische Hochschule Brandenburg Theodor Fontane (DE)
- Hamad Medical Corporation (QA)
Publication Details
- Journal
- BDJ Open
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1038/s41405-025-00370-4
- Citations
- 1
- Primary Topic
- Periodontal Regeneration and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.84