Factors affecting etiology and En-DCR outcomes in nasolacrimal duct obstruction: a retrospective cohort study
NLDO frequently coexists with comorbidities including paranasal sinusitis/nasal polyps, chronic conjunctivitis, dry eye, GERD, family history of epistaxis, and sleep-disordered breathing (sleep apnea/snoring). Notably, ROPLAS sign and minimum lacrimal sac diameter ≤ 3 mm on dacryocystography independently predict En-DCR outcomes, with the latter demonstrating a particularly strong association (OR = 8.71, p < 0.001). These findings highlight the importance of preoperative assessment of lacrimal sac anatomy and clinical signs in optimizing surgical success.
Authors
- Xinyue Yu (ORCID: https://orcid.org/0000-0001-5356-5177)
- Shuiling Li
- Yongqing Shen (ORCID: https://orcid.org/0000-0002-3783-3984)
- Huangxuan Shen (ORCID: https://orcid.org/0000-0002-6552-9541)
- Meiqing Chen
- Xuanwei Liang (ORCID: https://orcid.org/0000-0001-5408-5538)
- Rongxin Chen (ORCID: https://orcid.org/0000-0003-4867-8331)
- Jing Zhao (ORCID: https://orcid.org/0000-0003-2248-2605)
- Xielan Kuang (ORCID: https://orcid.org/0000-0002-0780-9799)
- Kerui Wang
- Yunming Liu
- Xuehua Liu
Institutions
- Sun Yat-sen University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1186/s40001-025-03162-6
- Citations
- 1
- Primary Topic
- Nasolacrimal Duct Obstruction Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- Natural Science Foundation of Guangdong Province