Comparative genomics of Shiga toxin-producing Escherichia coli reveals host-specific adhesiome adaptations in humans and cattle
Our findings provide new insights into STEC host adaptation and highlight potential targets to reduce zoonotic transmission and improve pre-harvest food safety strategies. Future research should focus on functional validation of host-specific adhesin variants and their potential as preventive strategies.
Authors
- Eduardo Méndez (ORCID: https://orcid.org/0000-0001-6897-319X)
- Vı́ctor Martı́nez (ORCID: https://orcid.org/0000-0002-1788-8793)
- Rodrigo Arancibia (ORCID: https://orcid.org/0000-0003-0689-9080)
- Gabriel Arriagada (ORCID: https://orcid.org/0000-0002-8810-1388)
- D Fernandez Luna
- Diego Méndez (ORCID: https://orcid.org/0000-0002-9866-4416)
- Jéssica Dörner (ORCID: https://orcid.org/0000-0001-5091-0465)
- Jorge Toledo (ORCID: https://orcid.org/0000-0001-8678-558X)
- Indira T. Kudva (ORCID: https://orcid.org/0000-0001-6750-7867)
- Nicolás Galarce (ORCID: https://orcid.org/0000-0002-4288-898X)
- Daniela Castro (ORCID: https://orcid.org/0000-0001-6923-5391)
- Beatriz Escobar (ORCID: https://orcid.org/0000-0001-9031-9418)
- Romina Ramos (ORCID: https://orcid.org/0000-0002-3732-7192)
- Joaquín Jorquera
- José T. Cartajena
- Nicolás Pizarro
Institutions
- Universidad de Santiago de Chile (CL)
- Agricultural Research Service (US)
- United States Department of Agriculture (US)
- Universidad Andrés Bello (CL)
- Catholic University of the Maule (CL)
- Instituto de Investigaciones Agropecuarias (CL)
- University of the Americas (CL)
- Universidad Santo Tomás (CL)
- National Animal Disease Center (US)
- University of O'Higgins (CL)
- Universidad de Aysén (CL)
- University of Chile (CL)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2025-10-09
- DOI
- https://doi.org/10.3389/fvets.2025.1639243
- Primary Topic
- Escherichia coli research studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Agriculture
- Agricultural Research Service
- Fondo Nacional de Desarrollo Científico y Tecnológico