The Guideline Uptake in Digital Ecosystems (GUIDE) study: protocol for implementation research on the impact of WHO SMART guidelines digital adaptation kits to improve quality of care
This research represents one of the first impact evaluations focused on integrating DAKs into existing national digital systems and the effect on service delivery outcomes. The mixed-methods study design will provide learnings for future scale-up and replication across other countries. We expect final results to be available in 2026, and preliminary findings will be shared at relevant fora. Trial registration https://www.isrctn.com/ISRCTN18394724 . Registration date: 21 December 2022.
Authors
- Shona Dalal (ORCID: https://orcid.org/0000-0003-1684-7452)
- Berhanu Fikadie Endehabtu (ORCID: https://orcid.org/0000-0001-7117-6407)
- Frances Baaba da-Costa Vroom
- Rosemary K Muliokela (ORCID: https://orcid.org/0000-0003-0614-3646)
- Justine Asante
- Binyam Tilahun (ORCID: https://orcid.org/0000-0002-1813-167X)
- Kafui Senya (ORCID: https://orcid.org/0000-0001-9168-2542)
- Özge Tunçalp (ORCID: https://orcid.org/0000-0002-5370-682X)
- Dominic Kwabena Atweam (ORCID: https://orcid.org/0000-0002-8630-8879)
- María Barreix (ORCID: https://orcid.org/0000-0003-3613-9672)
- Samuel Dery (ORCID: https://orcid.org/0000-0002-5076-6704)
- Adane Nigusie Weldeab (ORCID: https://orcid.org/0000-0003-0321-8542)
- Ernest Maya (ORCID: https://orcid.org/0000-0001-6050-6837)
- Kassu Ketema Gurmu (ORCID: https://orcid.org/0000-0001-8997-9072)
- Nancy Kidula (ORCID: https://orcid.org/0000-0002-3447-244X)
- Natschja Ratanaprayul (ORCID: https://orcid.org/0000-0003-0085-2900)
- Seth Kwaku Afagbedzi (ORCID: https://orcid.org/0000-0002-4566-8296)
- Lale Say (ORCID: https://orcid.org/0000-0002-1377-1328)
- Sarai Malumo (ORCID: https://orcid.org/0000-0001-5212-9963)
- Abdulaziz Mohammed Hussen (ORCID: https://orcid.org/0000-0003-1609-8498)
- Hanna Abayneh Telake (ORCID: https://orcid.org/0009-0001-0623-8808)
- Chris Guure (ORCID: https://orcid.org/0000-0001-6768-8215)
- Will Probert
- Soe Soe Thwin
- Tigest Tamrat
- Angela Abroso
- Haimanot Ambelu Workineh
- Gabriela Garcia-Camacho
Institutions
- World Health Organization - Pakistan (PK)
- University of Ghana (GH)
- University Medical Center Utrecht (NL)
- World Health Organization (CH)
- Ghana Health Service (GH)
- University of Gondar (ET)
Publication Details
- Journal
- Health Research Policy and Systems
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1186/s12961-025-01397-7
- Primary Topic
- Health Systems, Economic Evaluations, Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Global Fund to Fight AIDS, Tuberculosis and Malaria
- UNICEF
- Amhara Regional Health Bureau
- Centers for Disease Control and Prevention