GYPC methylation performance in detecting cervical (pre)cancer in high-risk HPV-positive women using liquid-based cervical scrapes
GYPC<sup>m</sup> has a higher CIN2 + OR and higher specificity and positive predictive value than cytology in HR-HPV-positive women and is a potential molecular biomarker for triaging HR-HPV (+) to detect cervical (pre)cancer.
Authors
- Zheming Tong (ORCID: https://orcid.org/0000-0002-4968-9174)
- Rong Wang (ORCID: https://orcid.org/0009-0000-3060-0750)
- Yu Fang (ORCID: https://orcid.org/0000-0001-6911-4047)
- Saiping Mao
- Xing Fan (ORCID: https://orcid.org/0009-0004-5639-0463)
Institutions
- Hunan Normal University (CN)
- Changsha Hospital for Maternal and Child Health Care (CN)
Publication Details
- Journal
- Infectious Agents and Cancer
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1186/s13027-025-00699-3
- Citations
- 1
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 1.35