The relationship between urine output and time to methotrexate clearance in pediatric leukemia patients receiving high-dose methotrexate therapy
Higher UO is associated with more efficient time to MTX clearance and shorter hospitalization in pediatric ALL patients receiving HD-MTX. Prospective studies are warranted to optimize supportive care protocols.
Authors
- Yi-Wen Hsiao (ORCID: https://orcid.org/0000-0002-9261-0353)
- Yi-Lun Wang (ORCID: https://orcid.org/0000-0002-0003-5153)
- Shih‐Hsiang Chen (ORCID: https://orcid.org/0000-0003-2588-2735)
- Tang‐Her Jaing (ORCID: https://orcid.org/0000-0002-5407-1555)
- Tsung‐Yen Chang (ORCID: https://orcid.org/0000-0003-1123-4235)
- Yu‐Chuan Wen
Institutions
- Chang Gung University (TW)
- Chang Gung Memorial Hospital (TW)
- Chang Gung Children's Hospital (TW)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1186/s12885-025-15064-1
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 0.00