Prevalence of Candidate Vaccine Targets and Genomic Features of Pediatric Invasive <i>Streptococcus Agalactiae</i> in Japan
This study suggests that current maternal GBS vaccine candidates would provide broad coverage for pediatric invasive infections in Japan. The identification of persistent and regionally disseminated lineages highlights the importance of investigating potential, yet, poorly understood, transmission routes, including environmental reservoirs, to inform future prevention strategies.
Authors
- Meiwa Shibata (ORCID: https://orcid.org/0000-0003-1477-1415)
- Kasumi Ishida‐Kuroki (ORCID: https://orcid.org/0000-0002-1694-3711)
- Yukihiro Akeda (ORCID: https://orcid.org/0000-0002-5325-4173)
- Kandai Nozu (ORCID: https://orcid.org/0000-0002-0290-3137)
- Masashi Kasai
- Satoshi Nakano (ORCID: https://orcid.org/0000-0002-8987-0250)
- Shogo Otake (ORCID: https://orcid.org/0000-0002-0084-9878)
- Yo Sugawara (ORCID: https://orcid.org/0000-0002-9897-3905)
- Motoyuki Sugai (ORCID: https://orcid.org/0000-0001-9252-7739)
- Shota Koide (ORCID: https://orcid.org/0000-0002-3970-9119)
Institutions
- National Institute of Infectious Diseases (JP)
- Kobe Children's Hospital (JP)
- Tokyo Metropolitan Children's Medical Center (JP)
- Kobe University (JP)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1093/infdis/jiaf491
- Primary Topic
- Neonatal and Maternal Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Agency for Medical Research and Development
- Ministry of Education, India
- University of Tokushima
- Nara Medical University
- Japan Society for the Promotion of Science