TNF-α gene expression in relation to TNF-α level and bone mineral density in Polish patients with celiac disease
In this study, TNF-<i>α</i>, both in terms of gene expression and serum level, does not appear to correlate with BMD status in individuals with CD and osteopenia/osteoporosis. Larger longitudinal studies integrating additional cytokines and signaling pathways are needed to clarify the role of TNF-α in bone loss in celiac disease.
Authors
- Agnieszka Dobrowolska (ORCID: https://orcid.org/0000-0002-3647-5070)
- Marta Kaczmarek-Ryś (ORCID: https://orcid.org/0000-0003-0173-5431)
- Michał Michalak (ORCID: https://orcid.org/0000-0002-2852-3984)
- Iwona Krela‐Kaźmierczak (ORCID: https://orcid.org/0000-0001-5122-8003)
- Kinga Skoracka (ORCID: https://orcid.org/0000-0002-1593-1903)
- Szymon Hryhorowicz (ORCID: https://orcid.org/0000-0003-4388-286X)
- Iga Dziechciowska
Institutions
- Poznan University of Medical Sciences (PL)
- Greater Poland Cancer Center (PL)
- Institute of Human Genetics (PL)
- Institute of Plant Genetics, Polish Academy of Sciences (PL)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-10-09
- DOI
- https://doi.org/10.3389/fendo.2025.1670590
- Primary Topic
- Celiac Disease Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Narodowa Agencja Wymiany Akademickiej