Safety Evaluation of Weight-Tiered, Anti-Xa-Guided Versus Fixed-Dose Enoxaparin Prophylaxis in Traumatic IntraCranial Hemorrhage (SAFE-ICH): A Retrospective Cohort Study
Higher initial enoxaparin doses and anti-Xa-driven adjustment were not associated with greater rates of tICH expansion in this study, albeit an overall low incidence. These findings highlight the multifactorial nature of TBI and tICH expansion.
Authors
- Brittany Curran
- Laura B. Ngwenya (ORCID: https://orcid.org/0000-0001-7103-971X)
- Carolyn Philpott (ORCID: https://orcid.org/0000-0002-0962-1001)
- Lauren Dehne (ORCID: https://orcid.org/0000-0001-6026-0750)
- Christopher Droege (ORCID: https://orcid.org/0000-0002-7609-8855)
- Madeline Foertsch
- Kiranpal S. Sangha
- Molly Droege (ORCID: https://orcid.org/0000-0002-4338-1021)
- Amy T. Makley
Institutions
- University of Cincinnati (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Annals of Pharmacotherapy
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1177/10600280251366325
- Primary Topic
- Venous Thromboembolism Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00