Determination the effect of Lavender ethanolic extract derived ointment on wound healing in Alloxan-induced diabetic Wistar rats

: The current study aimed to determine the effect of using different levels of lavender diethyl ether extract-derived ointment on wound healing in alloxan-induced diabetic Wistar rats. For a reason the twenty experimental rats at the age of three month were divided randomly in five groups whereas normal rats were treated with simple ointment base; diabetic rats were treated with simple ointment base as control, diabetic rats were treated with simple ointment base containing extracts (2.5% and 5%) and the diabetic rats received the nitrofurazone drug at 250 mg/kg dose per day for all treatments. The efficacy of wound healing treatment was evaluated based on wound area relative and histopathological characteristics. Data from the current study showed that the extract-treated diabetic animals showed a significant reduction in the wound area when compared with the control. In addition, histological studies of the tissue obtained on days 10 th and 20 th from the extract treated with the extract of lavender showed increased well-organized bands of collagen, more fibroblasts, and fewer inflammatory cells. In conclusion, we may demonstrate that the extract of lavender effectively stimulates wound contraction as compared to the control group and others, and it has accelerated wound healing in Alloxan-induced diabetic male Wistar rats.