Preparation, characterization and application of MT@SP@GBP and their use for synthesis of novel pyrazolophthalazine-5,10-diones
A series of azo-linked pyrazolophthalazine-5,10-diones (APPDs) were synthesized via multicomponent reaction of phthalic anhydride, synthetized azo-aldehyde, malononitrile, and hydrazine hydrate using the gabapentin (GBP) functionalized silica coated Fe<sub>3</sub>O<sub>4</sub> magnetic nano composites (MT@SP@GBP MNCs) as a catalyst. All derivatives were characterized by FT-IR, <sup>1</sup>H NMR, <sup>13</sup>C NMR, and mass spectrometry. MT@SP@GBP MNCs was characterized by FT-IR, FE-SEM, TEM, TGA, XRD, EDX and VSM.
Authors
- Leila Zare Fekri (ORCID: https://orcid.org/0000-0002-0525-3985)
- Mohammad Nikpassand (ORCID: https://orcid.org/0000-0002-9692-6849)
- Zahra Alizadeh
- Masoud Mokhtary (ORCID: https://orcid.org/0000-0003-3763-7139)
Institutions
- Islamic Azad University Rasht Branch (IR)
- Payame Noor University (IR)
Publication Details
- Journal
- Scientific Reports
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1038/s41598-025-19325-8
- Primary Topic
- Multicomponent Synthesis of Heterocycles
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Islamic Azad University