Proteasome regulation of petite-negativity in fission yeast
ptp1-1 is a partial loss of function mutation of the proteasome that enables growth of cells devoid of mitochondrial DNA through a mechanism that is independent of mitochondrial membrane potential rescue and associated with proteasome-dependent regulation of mitochondrial protein import precursors and the oxidative stress response.
Authors
- Mikel Zaratiegui (ORCID: https://orcid.org/0000-0002-0342-0268)
- Susanne Cranz-Mileva
- Katie Lin Amberg
- Lyrica Hao
Institutions
- Rutgers, The State University of New Jersey (US)
Publication Details
- Journal
- BMC Biology
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1186/s12915-025-02409-2
- Primary Topic
- Ubiquitin and proteasome pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bristol-Myers Squibb Foundation
- Rutgers Cancer Institute of New Jersey
- Rutgers, The State University of New Jersey