First report of pfhrp2 and pfhrp3 gene deletions compromising HRP2-based malaria rapid diagnostic tests in Malawi
This study is the first to report pfhrp2/3 gene deletions in Malawi. The presence of these deletions may compromise the performance of HRP2-based RDTs, indicating the need to reassess diagnostic strategies in affected regions.
Authors
- Se Jin Lee (ORCID: https://orcid.org/0000-0002-8626-6250)
- Wanjoo Chun
- Jin‐Hee Han (ORCID: https://orcid.org/0000-0003-0836-6675)
- Fauzi Muh (ORCID: https://orcid.org/0000-0002-3966-9110)
- Hojong Jun (ORCID: https://orcid.org/0009-0009-8364-3047)
- Sunghun Na (ORCID: https://orcid.org/0000-0002-2803-8356)
- Wang-Jong Lee (ORCID: https://orcid.org/0000-0003-2152-8915)
- Ernest Mazigo (ORCID: https://orcid.org/0000-0002-8044-7384)
- Johnsy Mary Louis (ORCID: https://orcid.org/0009-0005-1896-9017)
- Won Sun Park (ORCID: https://orcid.org/0000-0001-5868-3797)
- Eun‐Taek Han (ORCID: https://orcid.org/0000-0003-1962-7199)
- Fadhila Fitriana
- Jadidan Hada Syahada
- Feng Lu (ORCID: https://orcid.org/0000-0002-9599-3716)
Institutions
- Diponegoro University (ID)
- Kangwon National University (KR)
- Kangwon National University Hospital (KR)
- National Institute for Medical Research (TZ)
- Yangzhou University (CN)
Publication Details
- Journal
- Infectious Diseases of Poverty
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1186/s40249-025-01368-8
- Citations
- 2
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 3.76
Funders
- National Research Foundation
- Korea Health Industry Development Institute
- National Research Foundation of Korea
- Ministry of Education, India