The association between gut microbiota and metabolic dysfunction-associated steatotic liver disease (MASLD): a case-control study
Significant differences in gut microbiota composition were observed between MASLD and control groups, including reduced SCFA-producing and increased pro-inflammatory bacteria. These findings highlight the microbiota's potential role in MASLD pathogenesis, though confirmation in larger cohorts is needed.
Authors
- Fateme Ettehad Marvasti
- Bagher Larijani
- Ali Nikparast (ORCID: https://orcid.org/0000-0003-2686-2584)
- Afshin Ostovar (ORCID: https://orcid.org/0000-0001-8670-5797)
- Golaleh Asghari (ORCID: https://orcid.org/0000-0002-7925-5158)
- Hanieh‐Sadat Ejtahed (ORCID: https://orcid.org/0000-0002-6395-4915)
- Seyed Davar Siadat (ORCID: https://orcid.org/0000-0002-6892-5603)
- Shirin Hasani‐Ranjbar (ORCID: https://orcid.org/0000-0002-5670-3536)
- Shima Shojaie
- Mohammad Hassan Sohouli
- Pejman Rohani (ORCID: https://orcid.org/0009-0002-9712-5581)
- Mohsen Shaygantabar (ORCID: https://orcid.org/0009-0006-5483-9495)
Institutions
- Pasteur Institute of Iran (IR)
- Iran University of Medical Sciences (IR)
- National Nutrition and Food Technology Research Institute (IR)
- Children's Medical Center (IR)
- Shahid Beheshti University of Medical Sciences (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- BMC Pediatrics
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1186/s12887-025-06144-z
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Tehran University of Medical Sciences and Health Services