Ex Vivo Quantification of Calcification Stiffness in Aortic Stenosis: Biomechanical Data from Resected Human Valves
Some nodules demonstrated marked reactive stress even at low strain levels, indicating strong resistance to compression with minimal deformation. This study provides reference data on the biomechanical stiffness of calcification in human AS.
Authors
- Koichi Maeda (ORCID: https://orcid.org/0000-0002-1102-111X)
- Kazuo Shimamura (ORCID: https://orcid.org/0000-0003-1481-0795)
- Takashi Shirakawa (ORCID: https://orcid.org/0000-0001-7352-1876)
- Ai Kawamura
- Shin Yajima (ORCID: https://orcid.org/0000-0001-5058-0267)
- Shigeru Miyagawa (ORCID: https://orcid.org/0000-0003-0015-6569)
- T Kawamura (ORCID: https://orcid.org/0000-0003-2985-0036)
- Daisuke Yoshioka (ORCID: https://orcid.org/0000-0002-5574-9495)
Institutions
- The University of Osaka (JP)
Publication Details
- Journal
- Annals of Biomedical Engineering
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1007/s10439-025-03869-x
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00