Changing Dynamics in Liver Allocation: Donor and Recipient Traits Pre- and Post Acuity Circle Implementation

Data from the National Standard Transplant Analysis and Research (STAR) file were analyzed for liver transplants performed between February 4, 2017, and February 3, 2023. Donor and recipient variables were assessed using chi-squared and t-tests. Geographic trends and changes in transplant volumes were analyzed. Results: Following the AC implementation, transplant volume rose by 10%, with a 558% national allocation increase and a 34% local allocation decrease (p<0.001), with an increase in average distance from the donor hospital to the transplant center. Cold ischemic time increased from 5.74 to six hours (p<0.001), while the average waitlist time decreased from 232 to 182 days (p<0.001). High-severity patients received more transplants, with MELD scores rising from 23.1 to 24.7 (p<0.001). Conclusions: The AC policy was associated with altered transplant allocation patterns, improved matching based on medical urgency, and reduced waitlist times. However, increased cold ischemic times and travel distances highlighted logistic challenges. While early trends show progress toward equity, further research is needed to address long-term effects and persistent geographic disparities.

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Publication Details

Journal
Cureus
Published
2025-10-09
DOI
https://doi.org/10.7759/cureus.94206
Primary Topic
Liver Disease and Transplantation
Type
article
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article

Changing Dynamics in Liver Allocation: Donor and Recipient Traits Pre- and Post Acuity Circle Implementation

John Rehder, Raymond I Okeke, David M. Bagley, Mark P. Yeager et al.
Cureus
Liver Disease and Transplantation
article

Changing Dynamics in Liver Allocation: Donor and Recipient Traits Pre- and Post Acuity Circle Implementation

John Rehder, Raymond I Okeke, David M. Bagley, Mark P. Yeager, Jahnavi Nadella, Yongchen Fang, Mustafa Nazzal, Daniel Sculley, Noor Alyasiry
article en

Abstract

Data from the National Standard Transplant Analysis and Research (STAR) file were analyzed for liver transplants performed between February 4, 2017, and February 3, 2023. Donor and recipient variables were assessed using chi-squared and t-tests. Geographic trends and changes in transplant volumes were analyzed. Results: Following the AC implementation, transplant volume rose by 10%, with a 558% national allocation increase and a 34% local allocation decrease (p<0.001), with an increase in average distance from the donor hospital to the transplant center. Cold ischemic time increased from 5.74 to six hours (p<0.001), while the average waitlist time decreased from 232 to 182 days (p<0.001). High-severity patients received more transplants, with MELD scores rising from 23.1 to 24.7 (p<0.001). Conclusions: The AC policy was associated with altered transplant allocation patterns, improved matching based on medical urgency, and reduced waitlist times. However, increased cold ischemic times and travel distances highlighted logistic challenges. While early trends show progress toward equity, further research is needed to address long-term effects and persistent geographic disparities.

CureusVol. 17(10)
Saint Louis University Hospital (US)
Openalex Percentile: Top 62%
Liver Disease and Transplantation
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Changing Dynamics in Liver Allocation: Donor and Recipient Traits Pre- and Post Acuity Circle Implementation — John Rehder, Raymond I Okeke, et al. · Cureus (2025) | TGRS Research Map | TGRS