Evaluating corneal biomechanics using intraocular pressure methods and finite element modeling: parameters study and parametric optimization

Abstract Examining and analyzing the eye to predict and treat related diseases are essential. Consequently, researchers and engineers have consistently worked on developing devices to better understand the eye’s behavior and have modeled various parts of the eye to enhance prediction and comprehension. This study aims to investigate the biomechanical behavior of the cornea and contact lens in the context of the Corvis tonometer, with the goal of improving its pressure measurement accuracy. To this end, the Corvis tonometer test is simulated for a contact lens with specified geometry, properties, internal pressure, and boundary conditions. Subsequently, the relationship between the applied internal pressure and the quantities reported by the Corvis tonometer is analyzed under varying internal pressures, geometries, and properties, and the influence of these inputs on the reported quantities is evaluated..This process offers ophthalmologists a novel and rapid method for measuring intraocular pressure. Finally, through an appropriate statistical sensitivity analysis, the effects of variations in factors such as thickness, curvature, and material properties on the output parameters of the Corvis tonometer are examined, and the influence of all parameters on pressure measurement accuracy is thoroughly investigated.