Tumor Microenvironment T-cell Heterogeneity and Prognostic Model Construction in Laryngeal Squamous Cell Carcinoma by Single-cell and Bulk RNA Sequencing
This study provides insights into T-cell heterogeneity in LSCC and establishes a validated prognostic risk model for predicting survival and therapeutic outcomes.
Authors
- Fenglei Liu
- Yuan Li (ORCID: https://orcid.org/0000-0002-1929-5465)
- Jianchao Wang (ORCID: https://orcid.org/0000-0002-8488-1903)
- Xudong Wei (ORCID: https://orcid.org/0000-0002-3325-0837)
- Xin Pan (ORCID: https://orcid.org/0000-0001-8852-8050)
- Chao Du (ORCID: https://orcid.org/0009-0005-1139-5612)
Institutions
- Southern University of Science and Technology (CN)
- Third Affiliated Hospital of Southern Medical University (CN)
- Gansu University of Traditional Chinese Medicine (CN)
- Gansu Provincial Hospital (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Computer Methods in Biomechanics & Biomedical Engineering
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1080/10255842.2025.2570515
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.00