Study of Cerebellar Network Dynamics in Patients with Poststroke Aphasia Based on Resting-State Functional MRI
Patients with poststroke aphasia exhibited a segregated cerebellar state with reduced intracerebellar connectivity and efficiency and an integrated state with enhanced connectivity and small-world properties, together with reduced variability in cerebellar-cortical connections to language- and cognition-related regions. These state-specific network alterations were linked to distinct behavioral domains independent of lesion volume, highlighting a dissociation between structural constraints and dynamic, lesion-independent plasticity.
Authors
- Shuixing Zhang (ORCID: https://orcid.org/0000-0001-7377-382X)
- Wenfeng Mai (ORCID: https://orcid.org/0000-0002-7188-5075)
- Yanhong Dai
- Yongqiang Shu (ORCID: https://orcid.org/0000-0002-5333-1423)
- Zhenye Luo (ORCID: https://orcid.org/0000-0002-7118-2855)
- Liting Chen (ORCID: https://orcid.org/0000-0002-7786-1226)
- Lifeng Li (ORCID: https://orcid.org/0000-0002-7492-4017)
- Xiaoyun Chen (ORCID: https://orcid.org/0000-0002-2276-5392)
- Chen Lv (ORCID: https://orcid.org/0000-0002-9427-7443)
- Zhuoming Chen
- Qun Fang
Institutions
- Nanchang University (CN)
- Changsha Medical University (CN)
- Hunan University (CN)
- Laboratoire d’Innovation pour les Technologies des Énergies Nouvelles et les nanomatériaux (FR)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- First Affiliated Hospital of Jinan University (CN)
- First Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- American Journal of Neuroradiology
- Published
- 2025-10-09
- DOI
- https://doi.org/10.3174/ajnr.a9030
- Citations
- 2
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.86