Risk Factors for Valvulopathy Among Childhood Cancer Survivors

In this case-control study, heart RT, anthracyclines, and platinum agents were associated with increased VHD risk in childhood cancer survivors. Risks from both RT and anthracyclines were amplified with age and follow-up, underscoring the need for long-term cardiac surveillance.

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Institutions

Publication Details

Journal
JAMA Oncology
Published
2025-10-09
DOI
https://doi.org/10.1001/jamaoncol.2025.3863
Citations
3
Primary Topic
Chemotherapy-induced cardiotoxicity and mitigation
Type
article
Field-Weighted Citation Impact
4.16
Controls
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article

Risk Factors for Valvulopathy Among Childhood Cancer Survivors

Peter Kaatsch, Elisabeth Cardis, Isabelle Aerts, Helena J. H. van der Pal et al.
3 citations
JAMA Oncology
Chemotherapy-induced cardiotoxicity and mitigation
4.16
article

Risk Factors for Valvulopathy Among Childhood Cancer Survivors

Peter Kaatsch, Elisabeth Cardis, Isabelle Aerts, Helena J. H. van der Pal, Claudia E. Kuehni, Gisela Michel, Zsuzsanna Jakab, Raoul C. Reulen, Roderick Skinner, Fabiën N. Belle, Brice Fresneau, Giao Vu‐Bezin, Elvira C van Dalen, Jop C. Teepen, D. Winter, Nadia Haddy, Boris Schwartz, Florent de Vathaire, Lorna Zadravec Zaletel, Carlotta Sacerdote, Rodrigue S. Allodji, Monica Terenziani, Ibrahima Diallo, Julianne Byrne, Edit Bárdi, G. Levitt, Lars Hjorth, Elizabeth A. M. Feijen, Momcilo Jankovic, Cécile M. Ronckers, Cristina Veres, Isabelle Thierry-Chef, Desiree Grabow, Francesca Bagnasco, Véronique Minard-Colin, Leontien C. M. Kremer, Mike Hawkins, Neige Journy, Rivalin Aho Glele
article en
3 citations

Abstract

In this case-control study, heart RT, anthracyclines, and platinum agents were associated with increased VHD risk in childhood cancer survivors. Risks from both RT and anthracyclines were amplified with age and follow-up, underscoring the need for long-term cardiac surveillance.

JAMA OncologyVol. 11(12)
University of Bern (CH), Johannes Kepler University of Linz (AT), University of Ljubljana (SI), Inserm (FR), University of Lucerne (CH), Universitat Pompeu Fabra (ES), Lund University (SE), Johannes Gutenberg University Mainz (DE), Université Paris Sciences et Lettres (FR), Université Paris-Saclay (FR), Royal Victoria Infirmary (GB), University Hospital of Bern (CH), Instituto de Salud Carlos III (ES), Istituto Giannina Gaslini (IT), Institut Gustave Roussy (FR), Institute of Oncology Ljubljana (SI), Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT), Centre de recherche en Epidémiologie et Santé des Populations (FR), Azienda Ospedaliera San Gerardo (IT), Department of Medical Sciences (RU), Laboratoire d'études sur les monothéismes (FR), St Anna Children's Hospital (AT), Princess Máxima Center (NL), Institute of Social and Preventive Medicine (CH), Skåne University Hospital (SE), Great North Children's Hospital (GB), Markusovszky Egyetemi Oktatókórház (HU), Barcelona Institute for Global Health (ES), Piedmont Reference Center for Epidemiology and Cancer Prevention (IT), Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (ES), Fondazione IRCCS Istituto Nazionale dei Tumori (IT), CURE Childhood Cancer (US), Boyne Research Institute (IE), NIHR Birmingham Biomedical Research Centre (GB), Newcastle University (GB)
Openalex Percentile: Top 5%
Chemotherapy-induced cardiotoxicity and mitigation
4.16
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