Reevaluation of Enlarged Vestibular Aqueduct
The results of this cohort study underscore the importance of periodic hearing surveillance and tailored genetic counseling for patients with EVA, offering substantial implications for prevention, management, and future gene therapy approaches. This study provides an extensive phenotypic and genotypic characterization of EVA, potentially advancing an understanding of its molecular underpinnings and clinical heterogeneity.
Authors
- Yi Jiang (ORCID: https://orcid.org/0000-0002-3725-0148)
- Chaoyue Zhao
- Yongyi Yuan (ORCID: https://orcid.org/0000-0002-7936-4776)
- Shasha Huang (ORCID: https://orcid.org/0000-0001-9324-0078)
- Guojian Wang (ORCID: https://orcid.org/0000-0001-5934-4594)
- Xiaoge Li (ORCID: https://orcid.org/0000-0002-7046-7787)
- Pu Dai (ORCID: https://orcid.org/0000-0003-0718-8889)
- Dongyang Kang (ORCID: https://orcid.org/0000-0003-1256-4156)
- Suyan Yang
- Qiuquan Wang (ORCID: https://orcid.org/0000-0002-9616-7360)
- Xin Zhang (ORCID: https://orcid.org/0000-0001-9511-4737)
- Chang Guo (ORCID: https://orcid.org/0009-0009-8437-6526)
- Xue Gao (ORCID: https://orcid.org/0000-0003-4305-1206)
- Mingyu Han (ORCID: https://orcid.org/0000-0002-8140-0537)
- Jinyuan Yang
Institutions
- Ministry of Education of the People's Republic of China (CN)
- Sichuan University (CN)
- Chinese PLA General Hospital (CN)
- Shantou University (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- First Affiliated Hospital of Shantou University Medical College (CN)
- Zhongshan Hospital of Xiamen University (CN)
Publication Details
- Journal
- JAMA Otolaryngology–Head & Neck Surgery
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1001/jamaoto.2025.2866
- Citations
- 2
- Primary Topic
- Hearing, Cochlea, Tinnitus, Genetics
- Type
- article
- Field-Weighted Citation Impact
- 2.93