A Case of Unusual Clinical Presentation and Progression of Endocrine Mucin-Producing Sweat Gland Carcinoma

Endocrine mucin-producing sweat gland carcinoma (EMPSGC), which most commonly affects periorbital skin in older women, is a rare skin tumour showing neuroendocrine differentiation. We present a 58-year-old lady with diabetes, hypertension, ischaemic heart disease, and a progressively enlarging, pruritic scalp lump along with a non-enlarging neck lump. Histopathological analysis confirmed EMPSGC with progression to mucinous adenocarcinoma. This case underscores the possibility of EMPSGC developing in uncommon anatomical locations and highlights the significance of precise diagnosis and effective management. Despite its rarity, EMPSGC is associated with an indolent clinical course and favourable prognosis when identified and treated appropriately.