Geniposide alleviates kidney fibrosis by targeting STAT3-HK2-mediated glycolysis
Our results showed that GP protected against renal fibrosis, possibly through inhibiting STAT3/HK2 signaling-mediated glucose metabolism in UUO mouse kidneys.
Authors
- Rui Shi
- Deguang Wang (ORCID: https://orcid.org/0000-0003-4936-8773)
- Mengqian Liu
- Xuerong Wang (ORCID: https://orcid.org/0000-0002-3040-9435)
- Xun-Liang Li
- Yvyv Zhu
- Wenman Zhao (ORCID: https://orcid.org/0000-0001-9846-242X)
- Ruifeng Wang
- Zhijuan Wang
- Jia-xin Zhu
- Yingting Zhu (ORCID: https://orcid.org/0000-0002-9682-1748)
- Xiao Jianping
Institutions
- Anhui Medical University (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- BMC Complementary Medicine and Therapies
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1186/s12906-025-05102-7
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Anhui Medical University
- University Natural Science Research Project of Anhui Province