STREAM-PRS: a multi-tool pipeline for streamlining polygenic risk score computation
Overall, STREAM-PRS provides an efficient framework for selecting the best PRS calculation strategy and helps bridge the portability gap within the PRS field. STREAM-PRS is available at https://github.com/SaraBecelaere/STREAM-PRS.
Authors
- Severine A.R.A. Vermeire (ORCID: https://orcid.org/0000-0001-9942-3019)
- Deborah Sarah Jans (ORCID: https://orcid.org/0000-0003-2791-2010)
- Yasmina Abakkouy (ORCID: https://orcid.org/0000-0002-6601-4048)
- Margaux David (ORCID: https://orcid.org/0000-0001-7806-8417)
- Isabelle Cleynen (ORCID: https://orcid.org/0000-0003-0857-7683)
- Sara Becelaere
Institutions
- Center for Human Genetics (US)
- KU Leuven (BE)
Publication Details
- Journal
- Genome Medicine
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1186/s13073-025-01539-0
- Citations
- 2
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 3.63
Funders
- Pfizer
- Crohn's and Colitis Foundation
- Agentschap Innoveren en Ondernemen
- Vlaams Supercomputer Centrum
- Fonds Wetenschappelijk Onderzoek
- Vlaamse regering