Thyroid disease and breast cancer, benign breast neoplasm: a two-sample Mendelian randomization study
The present MR study explains the association between thyroid diseases and BC (mainly in HER2-positive BC). Furthermore, it demonstrates that hyperthyroidism, low levels of TSH, and TC may contribute to the development of benign breast neoplasm.
Authors
- Ming Yang (ORCID: https://orcid.org/0000-0002-4901-840X)
- Bowen Wang (ORCID: https://orcid.org/0000-0002-9685-5948)
- Ling Yue (ORCID: https://orcid.org/0000-0001-6476-0189)
- Yinuo Zhang (ORCID: https://orcid.org/0000-0001-8956-7334)
- Hui Zhang (ORCID: https://orcid.org/0000-0001-6825-5649)
- Yang Liu (ORCID: https://orcid.org/0000-0003-4559-5119)
- Jiacheng Yuan (ORCID: https://orcid.org/0000-0002-3679-7539)
Institutions
- Jilin University (CN)
- First Hospital of Jilin University (CN)
- Second Affiliated Hospital of Jilin University (CN)
Publication Details
- Journal
- BMC Women s Health
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1186/s12905-025-04046-x
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00