Idiopathic granulomatous lobular mastitis emulating breast carcinoma: a case report

Idiopathic granulomatous lobular mastitis is a rare and diagnostically challenging condition that clinically and radiologically mimics breast carcinoma. A high index of clinical suspicion is required for diagnosis. Histopathology is recommended over clinical imaging studies if idiopathic granulomatous lobular mastitis or breast cancer are suspected. Due to the rarity of this condition, this case report provides valuable insight into the diagnostic approach, differential diagnosis, associated radiological and histopathological findings, and treatment options, and also serves as a reference for successful treatment of idiopathic granulomatous lobular mastitis using conservative local and systemic immunosuppressive therapies with no clinical relapse for 3 years. Multidisciplinary approach is needed to prevent diagnostic delay and provide optimal therapeutic management and outcome.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2025-10-09
DOI
https://doi.org/10.1186/s13256-025-05548-w
Citations
2
Primary Topic
Breast Lesions and Carcinomas
Type
article
Field-Weighted Citation Impact
2.94

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article

Idiopathic granulomatous lobular mastitis emulating breast carcinoma: a case report

Martin Steinhoff, Haya Al-Merekhi, Samya Abu Shaikha, Hanof Ahmed
2 citations
Journal of Medical Case Reports
Breast Lesions and Carcinomas
2.94
article

Idiopathic granulomatous lobular mastitis emulating breast carcinoma: a case report

Martin Steinhoff, Haya Al-Merekhi, Samya Abu Shaikha, Hanof Ahmed
article en
2 citations

Abstract

Idiopathic granulomatous lobular mastitis is a rare and diagnostically challenging condition that clinically and radiologically mimics breast carcinoma. A high index of clinical suspicion is required for diagnosis. Histopathology is recommended over clinical imaging studies if idiopathic granulomatous lobular mastitis or breast cancer are suspected. Due to the rarity of this condition, this case report provides valuable insight into the diagnostic approach, differential diagnosis, associated radiological and histopathological findings, and treatment options, and also serves as a reference for successful treatment of idiopathic granulomatous lobular mastitis using conservative local and systemic immunosuppressive therapies with no clinical relapse for 3 years. Multidisciplinary approach is needed to prevent diagnostic delay and provide optimal therapeutic management and outcome.

Journal of Medical Case ReportsVol. 19(1)
Cornell University (US), Weill Cornell Medical College in Qatar (QA), Weill Cornell Medicine (US), Hamad Medical Corporation (QA), Qatar University (QA)
Hamad Medical Corporation, Medical Research Council
Openalex Percentile: Top 8%
Breast Lesions and Carcinomas
2.94
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Idiopathic granulomatous lobular mastitis emulating breast carcinoma: a case report — Martin Steinhoff, Haya Al-Merekhi, et al. · Journal of Medical Case Reports (2025) | TGRS Research Map | TGRS