Systemic inflammation biomarkers can identify high tumor mutation burden in lung adenocarcinoma
This study reveals distinct mutational characteristics among different TMB groups in Chinese lung adenocarcinoma patients and demonstrates that systemic inflammatory markers can serve as preliminary indicators for identifying high TMB lung cancer populations.
Authors
- Qiongyao Zhang (ORCID: https://orcid.org/0000-0003-0100-0099)
- Hongru Li (ORCID: https://orcid.org/0000-0001-8298-0513)
- Nengluan Xu (ORCID: https://orcid.org/0000-0002-2809-6548)
- Qing Li (ORCID: https://orcid.org/0000-0003-2652-6070)
- Yusheng Chen (ORCID: https://orcid.org/0000-0001-5292-1301)
- Xiaojie Yang (ORCID: https://orcid.org/0000-0003-0704-6776)
- Jiabin Fang
Institutions
- Fujian Medical University (CN)
- Fujian Provincial Hospital (CN)
- Fuzhou University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1186/s12885-025-14894-3
- Citations
- 2
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Fujian Province