Distinct genomic subgroups and mutational patterns in undifferentiated/dedifferentiated endometrial carcinoma
Our analysis revealed distinct architectures and actionable alterations in UDEC. The identification of molecular subgroups provides a promising framework for prognostic stratification. Collectively, our findings not only advance our understanding of UDEC biology but also illuminate potential translational applications.
Authors
- An‐Shine Chao (ORCID: https://orcid.org/0000-0002-1293-2230)
- Hsiu‐Jung Tung (ORCID: https://orcid.org/0000-0002-6160-6124)
- Chenyang Huang (ORCID: https://orcid.org/0000-0002-1956-6229)
- Angel Chao (ORCID: https://orcid.org/0000-0003-3834-2754)
- Chyong‐Huey Lai (ORCID: https://orcid.org/0000-0002-9977-9645)
- Ren‐Chin Wu (ORCID: https://orcid.org/0000-0003-1439-0874)
- Chiao‐Yun Lin (ORCID: https://orcid.org/0000-0002-1256-7018)
- Steve Rozen (ORCID: https://orcid.org/0000-0002-4288-0056)
- Chen-Bin Chang
Institutions
- Duke University (US)
- Chang Gung University (TW)
- Chang Gung Memorial Hospital (TW)
- Taipei Municipal YangMing Hospital (TW)
- Linkou Chang Gung Memorial Hospital (TW)
- Taipei City Hospital (TW)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1186/s12885-025-15053-4
- Citations
- 1
- Primary Topic
- Chromatin Remodeling and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Chang Gung Medical Foundation
- National Science and Technology Council