Recrudescent severe malaria due to Plasmodium falciparum following treatment in a Taiwanese patient: a case report
This case highlights that even with prompt, guideline-based therapy and the absence of pfk13 mutations, severe P. falciparum malaria in non-immune individuals can still develop recrudescence. Enhanced clinical vigilance, laboratory monitoring, and multidisciplinary care are essential for management. Reporting such rare recrudescent cases supports clinical awareness, informs best practice, and strengthens public health preparedness in low-incidence regions.
Authors
- Chiung-Tzu Hsiao
- Shih-Fen Hsu
- Po‐Ren Hsueh (ORCID: https://orcid.org/0000-0002-7502-9225)
- Yu‐Chuan Tseng (ORCID: https://orcid.org/0000-0001-8226-0989)
- Mengyu Cheng (ORCID: https://orcid.org/0000-0003-0893-2083)
- Jen-Jen Hsu (ORCID: https://orcid.org/0000-0002-7006-9471)
- Yi‐Cheng Shen (ORCID: https://orcid.org/0000-0001-5459-5378)
- Peter Bor‐Chian Lin (ORCID: https://orcid.org/0000-0002-8954-9045)
- Mao-Wang Ho
Institutions
- China Medical University (TW)
- Washington University in St. Louis (US)
- Hope Center for Neurological Disorders (US)
- China Medical University Hospital (TW)
Publication Details
- Journal
- Malaria Journal
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1186/s12936-025-05581-6
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- China Medical University Hospital
- China Medical University
- Centers for Disease Control and Prevention