Prolonged Postnatal Hypoxia Impairs Lung Development and Causes Severe Pulmonary Hypertension in Mice
This mouse model of prolonged hypoxia beginning early after birth offers a novel approach to explore treatments for pediatric pulmonary hypertension linked to abnormalities in lung development.
Authors
- L. Zazzeron (ORCID: https://orcid.org/0000-0001-9169-1262)
- Paul Lichtenegger (ORCID: https://orcid.org/0000-0002-3171-794X)
- Kakeru Shimoda (ORCID: https://orcid.org/0000-0002-6984-9016)
- Donald B. Bloch (ORCID: https://orcid.org/0000-0002-6828-4754)
- Jiayi Kang (ORCID: https://orcid.org/0000-0001-7784-6432)
- Fumito Ichinose (ORCID: https://orcid.org/0000-0003-4535-1632)
- Eizo Marutani (ORCID: https://orcid.org/0000-0001-7031-7386)
- Alexandra Marenco
- Haobo Li (ORCID: https://orcid.org/0000-0002-5660-7835)
- Elizabeth Hernández Moore
- Helena Tattersfield
Institutions
- Harvard University (US)
- Massachusetts General Hospital (US)
- Center for Pain and the Brain (US)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1161/jaha.125.042608
- Citations
- 2
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 3.04