A Case of Successful Conversion Surgery for <i>BRCA</i>-Mutated Pancreatic Body-Tail Cancer with Multiple Liver Metastases Subsequent to Positive Response to Olaparib Maintenance Therapy after Modified FOLFIRINOX

We report the very rare case of a patient with <i>BRCA</i>-positive PDAC with multiple liver metastases who underwent conversion surgery after treatment with mFFX and olaparib, achieved a pCR, and has remained recurrence-free for 2 years.

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Publication Details

Journal
Surgical Case Reports
Published
2025-01-01
DOI
https://doi.org/10.70352/scrj.cr.25-0372
Primary Topic
Grief, Bereavement, and Mental Health
Type
article
Field-Weighted Citation Impact
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A Case of Successful Conversion Surgery for BRCA-Mutated Pancreatic Body-Tail Cancer with Multiple Liver Metastases Subsequent to Positive Response to Olaparib Maintenance Therapy after Modified FOLFIRINOX

Kazuto Shibuya, Noriko Okuno, Toru Watanabe, Naoko Kimura et al.
Surgical Case Reports
Grief, Bereavement, and Mental Health
article

A Case of Successful Conversion Surgery for BRCA-Mutated Pancreatic Body-Tail Cancer with Multiple Liver Metastases Subsequent to Positive Response to Olaparib Maintenance Therapy after Modified FOLFIRINOX

Kazuto Shibuya, Noriko Okuno, Toru Watanabe, Naoko Kimura, Kenichi Hirabayashi, Yuuko Tohmatsu, Katsuhisa Hirano, Isaku Yoshioka, Kenta Yagi, Tsutomu Fujii
article en

Abstract

We report the very rare case of a patient with <i>BRCA</i>-positive PDAC with multiple liver metastases who underwent conversion surgery after treatment with mFFX and olaparib, achieved a pCR, and has remained recurrence-free for 2 years.

Surgical Case ReportsVol. 11(1)
University of Toyama (JP)
Openalex Percentile: Top 60%
Grief, Bereavement, and Mental Health
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