Alpha defensin immunoassay is more effective for ruling out rather than diagnosing periprosthetic joint infection (PJI): a prospective cohort study
While the alpha defensin immunoassay is not recommended to be used routinely as a screening method for PJI, its high specificity and NPV make it a valuable addition to traditional blood and synovial parameters in the diagnosis of complex hip and knee PJI, particularly for ruling out infection.
Authors
- Mohammed Anter Abdelhameed (ORCID: https://orcid.org/0000-0002-0575-1706)
- Dalia Tarik Kamal (ORCID: https://orcid.org/0000-0001-6917-7224)
- Amal Hosni (ORCID: https://orcid.org/0000-0001-7270-8655)
- Mohammad Kamal Abdelnasser
- Mohamed Moustafa
- Osama Osman
- Ayat Bakhet
Institutions
- Assiut University Hospitals (EG)
- Assiut University (EG)
Publication Details
- Journal
- Arthroplasty
- Published
- 2025-10-07
- DOI
- https://doi.org/10.1186/s42836-025-00337-8
- Citations
- 1
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.01