Applications of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) in heterocyclic ring formations
1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU), a commercially readily available and easily handled bicyclic amidine base, is a renowned organic strong base and deprotonating agent with nucleophilic characteristics that has gained considerable significance in organic synthesis in recent years due its selectivity (chemo-, regio-, and stereo-); hence, this review article provides a concise update on several types of heterocyclic rings (spiro, fused/bridged, simple) synthesized using important techniques with DBU as a catalyst, solvent, base, or reactant, from June 2022 until the present.
Authors
- Mohammed Mujahid Alam (ORCID: https://orcid.org/0000-0003-1585-3842)
- Ravi Varala (ORCID: https://orcid.org/0000-0002-6466-9454)
- K Achari (ORCID: https://orcid.org/0000-0002-7343-8455)
- Mohamed Hussein (ORCID: https://orcid.org/0009-0005-2114-7540)
Institutions
- University of Delhi (IN)
- INTI International University (MY)
- Aurobindo Pharma (India) (IN)
- King Khalid University (SA)
Publication Details
- Journal
- Organic & Biomolecular Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5ob01209k
- Citations
- 2
- Primary Topic
- Synthetic Organic Chemistry Methods
- Type
- article
- Field-Weighted Citation Impact
- 1.87