Applications of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) in heterocyclic ring formations

1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU), a commercially readily available and easily handled bicyclic amidine base, is a renowned organic strong base and deprotonating agent with nucleophilic characteristics that has gained considerable significance in organic synthesis in recent years due its selectivity (chemo-, regio-, and stereo-); hence, this review article provides a concise update on several types of heterocyclic rings (spiro, fused/bridged, simple) synthesized using important techniques with DBU as a catalyst, solvent, base, or reactant, from June 2022 until the present.

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Publication Details

Journal
Organic & Biomolecular Chemistry
Published
2025-01-01
DOI
https://doi.org/10.1039/d5ob01209k
Citations
2
Primary Topic
Synthetic Organic Chemistry Methods
Type
article
Field-Weighted Citation Impact
1.87
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article

Applications of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) in heterocyclic ring formations

Mohammed Mujahid Alam, Ravi Varala, K Achari, Mohamed Hussein
2 citations
Organic & Biomolecular Chemistry
Synthetic Organic Chemistry Methods
1.87
article

Applications of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) in heterocyclic ring formations

Mohammed Mujahid Alam, Ravi Varala, K Achari, Mohamed Hussein
article en
2 citations

Abstract

1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU), a commercially readily available and easily handled bicyclic amidine base, is a renowned organic strong base and deprotonating agent with nucleophilic characteristics that has gained considerable significance in organic synthesis in recent years due its selectivity (chemo-, regio-, and stereo-); hence, this review article provides a concise update on several types of heterocyclic rings (spiro, fused/bridged, simple) synthesized using important techniques with DBU as a catalyst, solvent, base, or reactant, from June 2022 until the present.

Organic & Biomolecular ChemistryVol. 23(41)
University of Delhi (IN), INTI International University (MY), Aurobindo Pharma (India) (IN), King Khalid University (SA)
Openalex Percentile: Top 13%
Synthetic Organic Chemistry Methods
1.87
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