Reduced ventromedial prefrontal cortex volume and impaired attention associated with past suicide attempts in patients with mood disorders
Reduced vmPFC volume and deficits in attention may be associated with history of suicidal behaviors in patients with MD. These findings support previous research highlighting the role of vmPFC in suicidal behavior and suggest that there may be specific cognitive subdomains that are particularly affected, offering potential intervention targets for future evaluation.
Authors
- Gitte M. Knudsen (ORCID: https://orcid.org/0000-0003-1508-6866)
- Vibe G. Frøkjær (ORCID: https://orcid.org/0000-0002-9321-2365)
- Kamilla Woznica Miskowiak (ORCID: https://orcid.org/0000-0003-2572-1384)
- Eduard Vieta (ORCID: https://orcid.org/0000-0002-0548-0053)
- Anjali Sankar (ORCID: https://orcid.org/0000-0002-7517-9776)
- Lars Vedel Kessing (ORCID: https://orcid.org/0000-0001-9377-9436)
- Julian Macoveanu (ORCID: https://orcid.org/0000-0001-6148-9477)
- Helena Andreu
Institutions
- University of Copenhagen (DK)
- Frederiksberg Hospital (DK)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Hospital Clínic de Barcelona (ES)
- Capital Region of Denmark (DK)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Journal of Psychiatric Research
- Published
- 2025-09-27
- DOI
- https://doi.org/10.1016/j.jpsychires.2025.09.040
- Primary Topic
- Suicide and Self-Harm Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- American Foundation for Suicide Prevention
- Lundbeckfonden