Late-Onset Para-Aortic Lymph Node Recurrence 11 Years after Resection of Pancreatic Cancer: Histological Reassessment Revealed Neuroendocrine Differentiation Amenable to Surgical Resection

This case highlights the importance of tissue diagnosis when late-onset recurrence is observed in patients with a prior diagnosis of PDAC. It also underscores the potential for extremely delayed recurrence in Pan-NENs and the importance of long-term surveillance. For patients presenting with isolated distant recurrence long after initial treatment for PDAC, biopsy and pathological re-evaluation should be considered to ensure appropriate therapeutic decision-making.

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Publication Details

Journal
Surgical Case Reports
Published
2025-01-01
DOI
https://doi.org/10.70352/scrj.cr.25-0374
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
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article

Late-Onset Para-Aortic Lymph Node Recurrence 11 Years after Resection of Pancreatic Cancer: Histological Reassessment Revealed Neuroendocrine Differentiation Amenable to Surgical Resection

Keiichi Akahoshi, Daisuke Ban, Satoshi� Matsui, Daisuke Asano et al.
Surgical Case Reports
Pancreatic and Hepatic Oncology Research
article

Late-Onset Para-Aortic Lymph Node Recurrence 11 Years after Resection of Pancreatic Cancer: Histological Reassessment Revealed Neuroendocrine Differentiation Amenable to Surgical Resection

Keiichi Akahoshi, Daisuke Ban, Satoshi� Matsui, Daisuke Asano, Yoko Tabe, Yoshiya Ishikawa, Yuko Kinowaki, Eriko Katsuta, Hiroki Ueda, Yuki Kato, Hayato Takamizawa
article en

Abstract

This case highlights the importance of tissue diagnosis when late-onset recurrence is observed in patients with a prior diagnosis of PDAC. It also underscores the potential for extremely delayed recurrence in Pan-NENs and the importance of long-term surveillance. For patients presenting with isolated distant recurrence long after initial treatment for PDAC, biopsy and pathological re-evaluation should be considered to ensure appropriate therapeutic decision-making.

Surgical Case ReportsVol. 11(1)
Tokyo Institute of Technology (JP), University of Tokyo Hospital (JP), Institute of Science Tokyo (JP), The University of Tokyo (JP)
Openalex Percentile: Top 61%
Pancreatic and Hepatic Oncology Research
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Late-Onset Para-Aortic Lymph Node Recurrence 11 Years after Resection of Pancreatic Cancer: Histological Reassessment Revealed Neuroendocrine Differentiation Amenable to Surgical Resection — Keiichi Akahoshi, Daisuke Ban, et al. · Surgical Case Reports (2025) | TGRS Research Map | TGRS