Giant retroperitoneal solitary neurofibroma

Solitary, benign retroperitoneal neurofibromas are exceedingly rare. Our case report highlights a man who presented with left-sided abdominal pain and left lower extremity numbness and weakness. On cross-sectional imaging, a 12.1 cm × 9.8 cm × 7.5 cm lobulated, well-marginated mass emanating from the left iliopsoas muscle at the level of the pelvic rim was visualised. A tissue biopsy suggested the diagnosis of a neurofibroma. The patient underwent resection of a femoral nerve sheath tumor, which resulted in femoral nerve palsy. Subsequent distal reconstructive surgeries and physical therapy resulted in improvement of his postoperative deficits. This is a highly rare case of a giant retroperitoneal solitary neurofibroma of the femoral nerve sheath diagnosed in a young patient.

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Publication Details

Journal
BMJ Case Reports
Published
2025-10-01
DOI
https://doi.org/10.1136/bcr-2024-263606
Primary Topic
Neurofibromatosis and Schwannoma Cases
Type
article
Field-Weighted Citation Impact
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Giant retroperitoneal solitary neurofibroma

Ross C. Puffer, Rathnayaka M. Kalpanee D. Gunasingha, Michele M. Gage, Katie Francine Lee et al.
BMJ Case Reports
Neurofibromatosis and Schwannoma Cases
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Giant retroperitoneal solitary neurofibroma

Ross C. Puffer, Rathnayaka M. Kalpanee D. Gunasingha, Michele M. Gage, Katie Francine Lee, Jonathan Keung, Benjamin Potter
article en

Abstract

Solitary, benign retroperitoneal neurofibromas are exceedingly rare. Our case report highlights a man who presented with left-sided abdominal pain and left lower extremity numbness and weakness. On cross-sectional imaging, a 12.1 cm × 9.8 cm × 7.5 cm lobulated, well-marginated mass emanating from the left iliopsoas muscle at the level of the pelvic rim was visualised. A tissue biopsy suggested the diagnosis of a neurofibroma. The patient underwent resection of a femoral nerve sheath tumor, which resulted in femoral nerve palsy. Subsequent distal reconstructive surgeries and physical therapy resulted in improvement of his postoperative deficits. This is a highly rare case of a giant retroperitoneal solitary neurofibroma of the femoral nerve sheath diagnosed in a young patient.

BMJ Case ReportsVol. 18(10)
Womack Army Medical Center (US), Walter Reed National Military Medical Center (US), Inova Fairfax Hospital (US), Penn Center for AIDS Research (US)
Openalex Percentile: Top 59%
Neurofibromatosis and Schwannoma Cases
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