Heart Transplantation for Amyloid Cardiomyopathy Has Comparable Outcomes With Other Etiologies: The UNOS Database

The number of heart transplants for ACM has increased in recent years, and overall outcomes in these ACM transplants have been similar compared to those for other cardiomyopathies. Despite historical concerns regarding poor prognosis and amyloid recurrence, carefully screened ACM patients can benefit from heart transplantation. Further research and optimization of ACM patient eligibility criteria alongside investigation of concurrent adjunctive therapies could optimize treatment of ACM with heart transplantation.

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Publication Details

Journal
Clinical Transplantation
Published
2025-10-01
DOI
https://doi.org/10.1111/ctr.70343
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Heart Transplantation for Amyloid Cardiomyopathy Has Comparable Outcomes With Other Etiologies: The UNOS Database

Dimitrios V. Avgerinos, Hilmi Alnsasra, Ilias P. Doulamis, Aspasia Tzani et al.
Clinical Transplantation
Amyloidosis: Diagnosis, Treatment, Outcomes
article

Heart Transplantation for Amyloid Cardiomyopathy Has Comparable Outcomes With Other Etiologies: The UNOS Database

Dimitrios V. Avgerinos, Hilmi Alnsasra, Ilias P. Doulamis, Aspasia Tzani, Rabea Asleh, Nicholas Steudel, Αlexandros Briasoulis, S. Rastogi, Ahmet Kılıç, Toshiki Kuno, Nikolaos Tepetes
article en

Abstract

The number of heart transplants for ACM has increased in recent years, and overall outcomes in these ACM transplants have been similar compared to those for other cardiomyopathies. Despite historical concerns regarding poor prognosis and amyloid recurrence, carefully screened ACM patients can benefit from heart transplantation. Further research and optimization of ACM patient eligibility criteria alongside investigation of concurrent adjunctive therapies could optimize treatment of ACM with heart transplantation.

Clinical TransplantationVol. 39(10)
Brigham and Women's Hospital (US), Mount Sinai Beth Israel (US), Lahey Hospital and Medical Center (US), Hebrew University of Jerusalem (IL), National and Kapodistrian University of Athens (GR), Hadassah Medical Center (IL), Lahey Medical Center (US), Onassis Cardiac Surgery Center (GR), Mayo Clinic in Florida (US), Johns Hopkins Hospital (US), Icahn School of Medicine at Mount Sinai (US)
Openalex Percentile: Top 75%
Amyloidosis: Diagnosis, Treatment, Outcomes
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Heart Transplantation for Amyloid Cardiomyopathy Has Comparable Outcomes With Other Etiologies: The UNOS Database — Dimitrios V. Avgerinos, Hilmi Alnsasra, et al. · Clinical Transplantation (2025) | TGRS Research Map | TGRS