Pseudolaric acid B induces G2/M phase arrest in canine mammary tumor cells by targeting CDK1
These findings not only expand the translational applicability of PAB in veterinary oncology but also identify CDK1 as a potential therapeutic vulnerability for combinatorial treatment strategies in CMTs.
Authors
- Hui Han (ORCID: https://orcid.org/0000-0003-0357-4651)
- Huixin Li (ORCID: https://orcid.org/0000-0001-6976-8323)
- Shanshan Xie (ORCID: https://orcid.org/0000-0003-4294-8169)
- Mengjuan Chen
- Xin Huang (ORCID: https://orcid.org/0000-0002-4741-5639)
- Mei-Jing Qin
- Qingda Meng
Institutions
- Henan Agricultural University (CN)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2025-10-09
- DOI
- https://doi.org/10.3389/fvets.2025.1644200
- Primary Topic
- Infectious Diseases and Mycology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Ministry of Human Resources and Social Security
- Henan Agricultural University