Image selection is critical in the dicentric chromosome assay in cytogenetic biodosimetry
Blood culture for 48 h permanent colcemid treatment increases the occurrence of over-condensed chromosomes, affecting Dic scoring. This study highlights the importance of proper training in metaphase image selection and structured education on quality assessment, including the use of specific microscope imaging and image processing software to ensure accurate biological dosimetry.
Authors
- Yohei Fujishima (ORCID: https://orcid.org/0000-0001-5053-3276)
- Hisako Suzuki
- Donovan Anderson (ORCID: https://orcid.org/0000-0001-6716-4059)
- Tomisato Miura (ORCID: https://orcid.org/0000-0003-3104-2134)
- Ayaka Okimoto
- Yui Kadowaki
Institutions
- Hirosaki University (JP)
Publication Details
- Journal
- International Journal of Radiation Biology
- Published
- 2025-10-08
- DOI
- https://doi.org/10.1080/09553002.2025.2566688
- Primary Topic
- Carcinogens and Genotoxicity Assessment
- Type
- article
- Field-Weighted Citation Impact
- 0.00