Clinical course of severe congenital aortic valve stenosis in children
This study highlights the vast heterogeneity of treatment pathways and outcomes in children diagnosed with severe VAS at different ages. The observed stabilization of severe VAS or regression of the serial peak Doppler gradient to mild-or-moderate VAS without symptoms in 24 children highlights the need for better insight into determinants of disease course.
Authors
- Pieter C. van de Woestijne (ORCID: https://orcid.org/0000-0003-0826-7837)
- Jolien W. Roos‐Hesselink (ORCID: https://orcid.org/0000-0002-6770-3830)
- Ad J.J.C. Bogers (ORCID: https://orcid.org/0000-0001-6200-1998)
- Maximiliaan L. Notenboom (ORCID: https://orcid.org/0000-0002-3828-6775)
- Kevin M. Veen (ORCID: https://orcid.org/0000-0003-2806-8384)
- Ingrid van Beynum
- Johanna J.M. Takkenberg (ORCID: https://orcid.org/0000-0001-9809-5623)
- Sezgin Albayrak (ORCID: https://orcid.org/0009-0007-4978-4669)
- Jonathan R.G. Etnel (ORCID: https://orcid.org/0000-0002-3960-8035)
- Willem A. Helbing (ORCID: https://orcid.org/0000-0002-1023-1537)
- Rebecca Swens
Institutions
- Erasmus MC (NL)
- Erasmus MC - Sophia Children’s Hospital (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- International Journal of Cardiology Congenital Heart Disease
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1016/j.ijcchd.2025.100626
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Erasmus Universitair Medisch Centrum Rotterdam