Visible‐Light‐Induced Cyclization of Vinyl Isocyanides with Diaryl Disulfides/1,2‐Dialkyldiselanes for the Synthesis of 1‐Substituted Isoquinolines

Isoquinoline compounds, especially 1‐substituted derivatives, have garnered considerable attention due to their ubiquitous presence in natural products and pharmaceuticals. Herein, a novel visible‐light‐induced tandem cyclization of vinyl isocyanides with diaryl disulfides or 1,2‐dialkyldiselanes has been developed. The reaction tolerates a wide range of substrates and provides an environmentally friendly route to the synthesis of 1‐thio/selenoisoquinolines from the easily available starting materials in a single step.