Composition of carotid plaques differs between Chinese and US patients: a histology study
The histology of Chinese plaques differs significantly from that of U.S. plaques, suggesting substantial differences in the pathophysiology of atherosclerotic cerebrovascular disease between Chinese and North American populations, which indicates a need for a different management approach.
Authors
- Hiroko Watase (ORCID: https://orcid.org/0000-0002-8951-7692)
- Binbin Sui (ORCID: https://orcid.org/0000-0002-1052-6992)
- Chun Yuan (ORCID: https://orcid.org/0000-0002-6154-5106)
- Thomas S. Hatsukami
- Randy Small
- Jie Sun (ORCID: https://orcid.org/0000-0001-9184-5049)
- Ted R. Kohler
- Daniel S. Hippe (ORCID: https://orcid.org/0000-0003-2427-4404)
- Haowen Li (ORCID: https://orcid.org/0000-0002-7526-5615)
- Marina S. Ferguson (ORCID: https://orcid.org/0000-0001-9141-2534)
- Dong Zhang (ORCID: https://orcid.org/0000-0002-0801-4971)
- Yajie Wang (ORCID: https://orcid.org/0009-0009-3650-7878)
- Yibin Wang (ORCID: https://orcid.org/0000-0003-0852-0767)
- Mi Shen
- Zirui Li (ORCID: https://orcid.org/0000-0002-6679-8006)
- Jingli Cao (ORCID: https://orcid.org/0000-0001-9819-3514)
- Roberto F. Nicosia
- Peiyi Gao
- J. Kevin DeMarco
- Xihai Zhao
Institutions
- Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa (ZA)
- Capital Medical University (CN)
- University of Washington (US)
- Walter Reed National Military Medical Center (US)
- Beijing Tian Tan Hospital (CN)
- Fred Hutch Cancer Center (US)
- National Clinical Research Center for Digestive Diseases (CN)
- Beijing Institute of Neurosurgery (CN)
- Beijing Ditan Hospital (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Chinese Neurosurgical Journal
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1186/s41016-025-00408-4
- Primary Topic
- Cerebrovascular and Carotid Artery Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- National Institutes of Health