Coronary Microvascular Dysfunction Related to Hydroxychloroquine-Induced Cardiomyopathy

This case establishes a new relationship between hydroxychloroquine cardiomyopathy and microvascular dysfunction. In addition to the cytotoxic effects of hydroxychloroquine, there may be an additional mechanism of vascular injury leading to the known manifestations with various electrical disturbances, and myocardial dysfunction.

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Publication Details

Journal
JACC Case Reports
Published
2025-10-01
DOI
https://doi.org/10.1016/j.jaccas.2025.105337
Citations
1
Primary Topic
Drug-Induced Ocular Toxicity
Type
article
Field-Weighted Citation Impact
1.71
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article

Coronary Microvascular Dysfunction Related to Hydroxychloroquine-Induced Cardiomyopathy

E. Kransdorf, Serguei Bannykh, C. Noel Bairey Merz, Donald E. Richards et al.
1 citations
JACC Case Reports
Drug-Induced Ocular Toxicity
1.71
article

Coronary Microvascular Dysfunction Related to Hydroxychloroquine-Induced Cardiomyopathy

E. Kransdorf, Serguei Bannykh, C. Noel Bairey Merz, Donald E. Richards, Louise Thomson, Deeksha Acharya
article en
1 citations

Abstract

This case establishes a new relationship between hydroxychloroquine cardiomyopathy and microvascular dysfunction. In addition to the cytotoxic effects of hydroxychloroquine, there may be an additional mechanism of vascular injury leading to the known manifestations with various electrical disturbances, and myocardial dysfunction.

JACC Case ReportsVol. 30(31)
Cedars-Sinai Medical Center (US), Cedars-Sinai Smidt Heart Institute (US)
Openalex Percentile: Top 13%
Drug-Induced Ocular Toxicity
1.71
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