Clinical Outcomes of Large-Bore Aspiration Thrombectomy for Tumor Pulmonary Embolism in Renal Cell Carcinoma

We present a 4-year longitudinal follow-up of a previously reported case involving a 66-year-old man with renal cell carcinoma who underwent radical nephrectomy, complicated by a massive pulmonary artery tumor embolism treated with large-bore aspiration thrombectomy. Serial clinical evaluations and imaging over 4 years have shown no evidence of disease recurrence following the initial intervention. This case underscores the evolving role of emergent large-bore aspiration thrombectomy in oncologic settings, not only as a therapeutic intervention but also for its diagnostic utility in enabling histopathologic characterization and guiding oncologic management. TAKE-HOME MESSAGES: Large-bore aspiration thrombectomy may offer long-term disease control in cases of tumor pulmonary embolism. This procedure can aid diagnosis and inform oncologic treatment planning through tissue acquisition.